EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.4.24.B12 | Abz-TEGEARGSVI-Dap(2,4-dinitrophenyl)-KK + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
- |
Mus musculus |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
- |
Bos taurus |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
cleavage site is Glu373-Ala374 |
Homo sapiens |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
cleavage site is Glu373-Ala374, other cleavage sites are Glu1545-Gly1546, Glu1819-Ala1820, and Glu1919-Leu1920 |
Homo sapiens |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
substrate from cartilage, extensive digestion, N-terminal cleavage sites between glutamate and small uncharged aliphatic amino acids in nonglycosylated regions of the aggregan core protein: the interglobular domain E373-A, and between chondroitin sulfate attachment sites 1 and 2 E1480-G |
Homo sapiens |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
substrate from cartilage, N-terminal cleavage sites between glutamate and small uncharged aliphatic amino acids in nonglycosylated regions of the aggregan core protein: the interglobular domain E373-A, and within the chondroitinsulfate 2 attachment region E1666-G, E1771-A, and E1871-L |
Bos taurus |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
degradation of cartilage matrix |
Homo sapiens |
? |
- |
? |
| 3.4.24.B12 | aggrecan + H2O |
enzyme may play a role in cartilage breakdown |
Homo sapiens |
? |
- |
? |
