EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.4.21.37 | (VGVAPG)2V + H2O |
human elastin exon 24-derived peptide substrate, hydrolysis by the enzyme occurs when its active site is fully occupied by the substrate, cleavage at Val-Ala and at Gly-Val bonds, the latter to a lesser extent |
Homo sapiens |
VGVAPGVGV + APGV + VGVAPG + VGVAPGV |
- |
? |
3.4.21.37 | (VGVAPG)3V + H2O |
human elastin exon 24-derived peptide substrate, hydrolysis by the enzyme occurs when its active site is fully occupied by the substrate, cleavage at Val-Ala and at Gly-Val bonds, the latter to a lesser extent |
Homo sapiens |
VGVAPGVGV + APGVGVAPGV + VGVAPGVGVAPGVGV + APGV + VGVAPG + VGVAPGVGVAPGV + GVAPGV |
- |
? |
3.4.21.37 | 1-ethyl-3,3-dimethyl-2-[(E)-2-[6-(2,2,3,3,3-pentafluoropropanamido)-2,3-dihydro-1H-xanthen-4-yl]ethenyl]-3H-indol-1-ium + H2O |
- |
Homo sapiens |
2-[(E)-2-(6-amino-2,3-dihydro-1H-xanthen-4-yl)ethenyl]-1-ethyl-3,3-dimethyl-3H-indol-1-ium + 2,2,3,3,3-pentafluoropropanal |
- |
ir |
3.4.21.37 | 2-(chloroacetyl)-3-naphthoic acid o-toluidide + H2O |
- |
Homo sapiens |
? |
- |
? |
3.4.21.37 | 2-aminobenzoyl-APEEIMDQQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O |
kcat/Km is 136times greater for neutrophil elastase than for proteinase 3 |
Homo sapiens |
2-aminobenzoyl-APEEI + MDQQ-N-(2,4-dinitrophenyl)ethylenediamine |
- |
? |
3.4.21.37 | 2-aminobenzoyl-APEEIMDRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O |
kcat/Km is 47times greater for neutrophil elastase than for proteinase 3 |
Homo sapiens |
2-aminobenzoyl-APEEI + MDRQ-N-(2,4-dinitrophenyl)ethylenediamine |
- |
? |
3.4.21.37 | 2-aminobenzoyl-APEEIMDRYQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O |
kcat/Km is 30times greater for neutrophil elastase than for proteinase 3 |
Homo sapiens |
2-aminobenzoyl-APEEI + MDRYQ-N-(2,4-dinitrophenyl)ethylenediamine |
- |
? |
3.4.21.37 | 2-aminobenzoyl-APEEIMDYQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O |
kcat/Km is 114times greater for neutrophil elastase than for proteinase 3 |
Homo sapiens |
2-aminobenzoyl-APEEI + MDYQ-N-(2,4-dinitrophenyl)ethylenediamine |
- |
? |
3.4.21.37 | 2-aminobenzoyl-APEEIMPRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O |
kcat/Km is over 11times greater for neutrophil elastase than for proteinase 3 |
Homo sapiens |
2-aminobenzoyl-APEEI + MPRQ-N-(2,4-dinitrophenyl)ethylenediamine |
- |
? |
3.4.21.37 | 2-aminobenzoyl-APEEIMRRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O |
kcat/Km is over 500times greater for neutrophil elastase than for proteinase 3 |
Homo sapiens |
2-aminobenzoyl-APEEI + MRRQ-N-(2,4-dinitrophenyl)ethylenediamine |
- |
? |