EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.2.2.27 | 3,N4-ethenocytosine-mismatched double-stranded DNA + H2O |
- |
Schizosaccharomyces pombe |
3,N4-ethenocytosine + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 3,N4-ethenocytosine-mismatched double-stranded DNA + H2O |
- |
Drosophila melanogaster |
3,N4-ethenocytosine + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 3,N4-ethenocytosine-mismatched single-stranded DNA + H2O |
- |
Homo sapiens |
3,N4-ethenocytosine + single-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-fluorouracil-mismatched double-stranded DNA + H2O |
- |
Schizosaccharomyces pombe |
5-fluorouracil + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-fluorouracil-mismatched double-stranded DNA + H2O |
- |
Drosophila melanogaster |
5-fluorouracil + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-fluorouracil-mismatched double-stranded DNA + H2O |
UDGb is active on 5-fluorouracil-G pairs |
Pyrobaculum aerophilum |
5-fluorouracil + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-formyluracil-mismatched double-stranded DNA + H2O |
- |
Homo sapiens |
5-formyluracil + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-formyluracil-mismatched single-stranded DNA + H2O |
- |
Homo sapiens |
5-formyluracil + single-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-hydroxymethyl-uracil-mismatched double-stranded DNA + H2O |
the preferred substrate of UDGb is hydroxymethyl-uracil mispaired with guanine, followed by G-U and A-U, UDGb is active on ethenocytosine-G and 5-fluorouracil-G pairs, and UDGb also performs processing of uracil and hydroxymethyluracil from single-stranded DNA, but highly prefers double-stranded DNA substrates |
Pyrobaculum aerophilum |
5-hydroxymethyl-uracil + double-stranded DNA with abasic site |
- |
? |
3.2.2.27 | 5-hydroxymethyl-uracil-mismatched single-stranded DNA + H2O |
the preferred substrate of UDGb is hydroxymethyl-uracil mispaired with guanine, followed by G-U and A-U, UDGb is active on ethenocytosine-G and 5-fluorouracil-G pairs, and UDGb also performs processing of uracil and hydroxymethyluracil from single-stranded DNA, but highly prefers double-stranded DNA substrates |
Pyrobaculum aerophilum |
5-hydroxymethyl-uracil + single-stranded DNA with abasic site |
- |
? |