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Results 1 - 4 of 4
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.8.2.363'-phosphoadenylyl sulfate + desulfo-A47934 the enzyme catalyzes the final step in the biosynthesis of the glycopeptide antibiotic A47934 Streptomyces toyocaensis adenosine 3',5'-bisphosphate + A47934 i.e. LY 154989 ?
Display the reaction diagram Show all sequences 2.8.2.363'-phosphoadenylyl sulfate + desulfo-A47934 100-fold preference for desulfo-A47934 over teicoplanin Streptomyces toyocaensis adenosine 3',5'-bisphosphate + A47934 i.e. LY 154989 ?
Display the reaction diagram Show all sequences 2.8.2.363'-phosphoadenylyl sulfate + teicoplanin the sulfated residue of sulfo-teicoplanin is not unambiguously identified. Based on the precedent with the A47934 fragmentation, it is concluded that His6-StaL preferentially sulfates the glycopeptide antibiotics on the N-terminal 4-hydroxy-L-phenylglycine residue Streptomyces toyocaensis adenosine 3',5'-bisphosphate + sulfo-teicoplanin - ?
Display the reaction diagram Show all sequences 2.8.2.363'-phosphoadenylyl sulfate + teicoplanin aglycone the sulfated residue of sulfo-teicoplanin is not unambiguously identified. Based on the precedent with the A47934 fragmentation, it is concluded that His6-StaL preferentially sulfates the glycopeptide antibiotics on the N-terminal 4-hydroxy-L-phenylglycine residue Streptomyces toyocaensis adenosine 3',5'-bisphosphate + sulfoteicoplanin aglycone - ?
Results 1 - 4 of 4