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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
2.7.7.50
2'-fluoro-2'-deoxy-GTP + pp(5')RNA
0.16fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
2'-fluoro-2'-deoxy-G(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
2-amino-6-chloropurine-beta-D-ribose triphosphate + pp(5')RNA
0.08fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
2-amino-6-chloropurine-beta-D-ribose-(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
3'-deoxy-GTP + pp(5')RNA
0.15fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
3'-deoxy-G(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
3'-O-methyl-GTP + mRNA
-
Saccharomyces cerevisiae
?
-
?
2.7.7.50
3'-O-methyl-GTP + pp(5')RNA
0.38fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
3'-O-methyl-G(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
5'-NAD-capped RNA + ?
NudC is a single-strand-specific RNA-decapping enzyme with a strong preference for a purine as first nucleotide. NudC prefers NAD-RNA over NAD(H) by several orders of magnitude. The enzyme has strong preference for RNAs with at least three unpaired nucleotides at their 5' ends
Escherichia coli
?
-
?
2.7.7.50
6-methylthio-GTP + pp(5')RNA
0.07fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
6-methylthio-G(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
6-thio-GTP + pp(5')RNA
0.16fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
6-thio-G(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
8-bromo-GTP + pp(5')RNA
0.40fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
8-bromo-G(5')ppp(5')RNA + diphosphate
-
?
2.7.7.50
8-iodoGTP + pp(5')RNA
1.0fold efficiency compared with substrate GTP
Paramecium bursaria Chlorella virus 1
8-iodo-G(5')ppp(5')RNA + diphosphate
-
?
Results
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10
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173
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