EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.7.49 | ((1s,3s)-3-(7-amino-2H-2,3,5,6-tetraazabenzo[cd]azulen-2-yl)cyclobutyl)methyl tetrahydrogen triphosphate + DNAn |
- |
Human immunodeficiency virus 1 |
diphosphate + DNAn+1 |
- |
? |
2.7.7.49 | ((2R,3S,5R)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate + DNAn |
- |
Human immunodeficiency virus 1 |
diphosphate + DNAn+1 |
- |
? |
2.7.7.49 | ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
- |
Human immunodeficiency virus 1 |
diphosphate + DNAn+1 |
- |
? |
2.7.7.49 | ((2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate + DNAn |
- |
Human immunodeficiency virus 1 |
diphosphate + DNAn+1 |
- |
? |
2.7.7.49 | ((2R,3S,5R)-5-(6-amino-8-(prop-2-yn-1-ylamino)-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate + DNAn |
- |
Human immunodeficiency virus 1 |
diphosphate + DNAn+1 |
- |
? |
2.7.7.49 | (-)-beta-2',3'-dideoxy-3'-thiacytidine triphosphate + 2-naphthyl-Tyr115 of p66 reverse transcriptase |
- |
Human immunodeficiency virus 1 |
? |
- |
? |
2.7.7.49 | (-)-beta-2',3'-dideoxy-3'-thiacytidine triphosphate + aminomethyl-Phe115 of p66 reverse transcriptase |
- |
Human immunodeficiency virus 1 |
? |
- |
? |
2.7.7.49 | (-)-beta-2',3'-dideoxy-3'-thiacytidine triphosphate + DNAn |
- |
Human immunodeficiency virus 1 |
diphosphate + ? |
- |
? |
2.7.7.49 | (-)-beta-2',3'-dideoxy-3'-thiacytidine triphosphate + Tyr115 of p66 reverse transcriptase |
- |
Human immunodeficiency virus 1 |
? |
- |
? |
2.7.7.49 | 2',3'-dideoxy-CTP + DNAn |
- |
Human immunodeficiency virus 1 |
diphosphate + DNAn+1 |
- |
? |