EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  2.5.1.B35 | (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate |
about 95% of the activity with geranylfarnesyl diphosphate. The main product is undecaprenyl diphosphate, regardless of the substrate. If the ratio of IPP to the allylic substrate becomes lower, the product will be shorter, probably because of the shortage of isopentenyl diphosphate or because of the frequent dissociation of an intermediate from the active site by competitive binding of the hydrophobic allylic substrate |
Aeropyrum pernix |
8 diphosphate + ditrans,octacis-undecaprenyl diphosphate |
the stereochemistry of the product is not experimentally determined |
? |
| 2.5.1.B35 | geranyl diphosphate + 9 isopentenyl diphosphate |
about 65% of the activity with geranylfarnesyl diphosphate. The main product is undecaprenyl diphosphate, regardless of the substrate. If the ratio of IPP to the allylic substrate becomes lower, the product will be shorter, probably because of the shortage of isopentenyl diphosphate or because of the frequent dissociation of an intermediate from the active site by competitive binding of the hydrophobic allylic substrate |
Aeropyrum pernix |
9 diphosphate + monotrans,nonacis-undecaprenyl diphosphate |
the stereochemistry of the product is not experimentally determined |
? |
| 2.5.1.B35 | geranylfarnesyl diphosphate + 6 isopentenyl diphosphate |
the enzyme is involved in the biosynthetic pathway for isoprenoid compounds |
Aeropyrum pernix |
6 diphosphate + tetratrans,hexacis-undecaprenyl diphosphate |
- |
? |
| 2.5.1.B35 | geranylfarnesyl diphosphate + 6 isopentenyl diphosphate |
geranylfarnesyl diphosphate is the most preferred allylic substrate. The main product is undecaprenyl diphosphate, regardless of the substrate. If the ratio of isopentenyl diphosphate to the allylic substrate becomes lower, the product will be shorter, probably because of the shortage of isopentenyl diphosphate or because of the frequent dissociation of an intermediate from the active site by competitive binding of the hydrophobic allylic substrate |
Aeropyrum pernix |
6 diphosphate + tetratrans,hexacis-undecaprenyl diphosphate |
the stereochemistry of the product is not experimentally determined |
? |
| 2.5.1.B35 | geranylgeranyl diphosphate + 7 isopentenyl diphosphate |
about 45% of the activity with geranylfarnesyl diphosphate. The main product is undecaprenyl diphosphate, regardless of the substrate. If the ratio of IPP to the allylic substrate becomes lower, the product will be shorter, probably because of the shortage of isopentenyl diphosphate or because of the frequent dissociation of an intermediate from the active site by competitive binding of the hydrophobic allylic substrate. When the ratio of isopentenyl diphosphate to geranylfarnesyl diphosphate is decreased to 1, the UPP synthase predominately yields shorter C3045 products |
Aeropyrum pernix |
7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate |
the stereochemistry of the product is not experimentally determined |
? |
| 2.5.1.B35 | more |
dimethylallyl diphosphate does not react with the enzyme. If the ratio of IPP to the allylic substrate becomes lower, the product will be shorter, probably because of the shortage of isopentenyl diphosphate or because of the frequent dissociation of an intermediate from the active site by competitive binding of the hydrophobic allylic substrate |
Aeropyrum pernix |
? |
- |
? |
