EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
- |
Sus scrofa |
7 diphosphate + all-trans-decaprenyl diphosphate |
- |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
- |
Gluconobacter oxydans |
7 diphosphate + all-trans-decaprenyl diphosphate |
- |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
- |
Aphis gossypii |
7 diphosphate + all-trans-decaprenyl diphosphate |
- |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
- |
Gluconobacter oxydans |
7 diphosphate + all-trans-decaprenyl diphosphate |
high product specificity for decaprenyl synthesis |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
- |
Paracoccus denitrificans |
7 diphosphate + all-trans-decaprenyl diphosphate |
plus minor amounts of undecaprenyl diphosphate |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
best substrate |
Cereibacter sphaeroides |
7 diphosphate + all-trans-decaprenyl diphosphate |
high product specificity for decaprenyl synthesis |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
key enzyme in synthesis of the decaprenyl tail in coenzyme Q10 |
Gluconobacter oxydans |
7 diphosphate + all-trans-decaprenyl diphosphate |
- |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
the enzyme catalyzes the consecutive condensation of isopentenyl diphosphate with allylic diphosphates to produce decaprenyl diphosphate, which is used for the side chain of ubiquinone Q10 |
Gluconobacter oxydans |
7 diphosphate + all-trans-decaprenyl diphosphate |
- |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
compared with other priming substrates examined (geranyl diphosphate, geranylgeranyl diphosphate), farnesyl diphosphate results in the highest values for the reaction rate and kcat/KM. Dimethylallyl diphosphate is not a suitable substrate |
Cereibacter sphaeroides |
7 diphosphate + all-trans-decaprenyl diphosphate |
decaprenyl diphosphate is the major product, other prenyl diphosphates comprise only minor components |
? |
2.5.1.91 | (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate |
a major intermediate product (GGPP) is produced during the consecutive condensation reaction starting from FPP and IPP, leading to the formation of the final product (DPP) by adding six more IPPs. The two-major step catalytic mechanism might be a biochemical feature of insect DPPSs |
Aphis gossypii |
7 diphosphate + all-trans-decaprenyl diphosphate |
- |
? |