EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    2.5.1.87 | (2E,6E)-farnesyl diphosphate + 13 isopentenyl diphosphate |
- |
Saccharomyces cerevisiae |
13 diphosphate + di-trans,poly-cis-hexadecaprenyl diphosphate |
di-trans,poly-cis-hexadecaprenyl diphosphate and di-trans,poly-cis-heptadecaprenyl diphosphate are the main products |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 13 isopentenyl diphosphate |
Rer2p Z-prenyltransferase synthesizes a well-defined family of polyprenols of 1318 isoprene residues with dominating C80 (16 isoprene residues) extending to C120. Two polyisoprenoid families with dominating C80 and C110 indicating the activity of both yeast Z-prenyltransferases Rer2p and Srt1p, respectively. The family of longer chain dolichols appearing in the stationary growth phase contains dolichols with even more than 50 isoprene units exhibiting monotonically decreasing amounts with increasing chain lengths. The family of shorter chain dolichols is characteristic of the Rer2p products synthesized during the logarithmic growth phase of yeast. It forms a well-defined family of dolichols with 1318 isoprene residues with a certain level of longer dolichols composed of up to 24 isoprene units |
Saccharomyces cerevisiae |
13 diphosphate + di-trans,poly-cis-hexadecaprenyl diphosphate |
- |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 13 isopentenyl diphosphate |
Rer2p Z-prenyltransferase synthesizes a well-defined family of polyprenols of 1318 isoprene residues with dominating C80 (16 isoprene residues) extending to C120 |
Saccharomyces cerevisiae |
13 diphosphate + di-trans,poly-cis-hexadecaprenyl diphosphate |
- |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 14 isopentenyl diphosphate |
- |
Saccharomyces cerevisiae |
14 diphosphate + di-trans,poly-cis-heptadecaprenyl diphosphate |
di-trans,poly-cis-hexadecaprenyl diphosphate and di-trans,poly-cis-heptadecaprenyl diphosphate are the main products |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 19 isopentenyl diphosphate |
- |
Saccharomyces cerevisiae |
19 diphosphate + di-trans,poly-cis-docosaprenyl diphosphate |
dominating polyprenol with 22 isoprene residues, Srt1p products reaching C290 indicate the failure of a strict bacterial-like chain length control |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 21 isopentenyl diphosphate |
trans,trans-farnesyl diphosphate is a better substrate than geranylgeranyl diphosphate. The enzyme catalyzes the formation of polyprenyl diphosphates with predominant carbon number C120. In vitro rubber biosynthesis analysis indicates that the Arabidopsis cis-prenyltransferase itself could not catalyze the formation of high molecular weight polyprenyl diphosphate such as natural rubber |
Arabidopsis thaliana |
21 diphosphate + di-trans,poly-cis tetracosaprenyl diphosphate |
- |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 21 isopentenyl diphosphate |
trans,trans-farnesyl diphosphate is a better substrate than geranylgeranyl diphosphate |
Arabidopsis thaliana |
21 diphosphate + di-trans,poly-cis tetracosaprenyl diphosphate |
the enzyme synthesizes polyisoprenes with carbon number higher than 90. The peak activity is observed at the point that corresponds to the polyisoprene with carbon number C120 |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate |
- |
Saccharomyces cerevisiae |
5 diphosphate + di-trans,poly-cis-octaprenyl diphosphate |
di-trans,poly-cis-octaprenyl diphosphate and di-trans,poly-cis-nonaprenyl diphosphate are the main products |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate |
the polyprenol product of Srt1p is longer in chain length than that of Rer2p and is not sufficiently converted to dolichol and dolichyl phosphate, unlike that of Rer2p |
Saccharomyces cerevisiae |
5 diphosphate + di-trans,poly-cis-octaprenyl diphosphate |
di-trans,poly-cis-octaprenyl diphosphate and di-trans,poly-cis-nonaprenyl diphosphate are the main products |
? |
| 2.5.1.87 | (2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate |
- |
Saccharomyces cerevisiae |
6 diphosphate + di-trans,poly-cis-nonaprenyl diphosphate |
di-trans,poly-cis-octaprenyl diphosphate and di-trans,poly-cis-nonaprenyl diphosphate are the main products |
? |
