EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.3 | 2-methyl-4-amino-5-diphosphomethylpyrimidine + 2-(4-methyl-1,3-thiazol-5-yl)ethyl phosphate |
involved in biosynthesis of thiamine |
Saccharomyces cerevisiae |
diphosphate + ? |
- |
? |
2.5.1.3 | 2-methyl-4-amino-5-diphosphomethylpyrimidine + 2-(4-methyl-1,3-thiazol-5-yl)ethyl phosphate |
involved in biosynthesis of thiamine |
Brassica napus |
diphosphate + ? |
- |
? |
2.5.1.3 | 2-methyl-4-amino-5-diphosphomethylpyrimidine + 2-(4-methyl-1,3-thiazol-5-yl)ethyl phosphate |
the bifunctional enzyme hydroxyethylthiazole kinase/thiamine-phosphate pyrophosphorylase catalyzes two sequential steps in the synthesis of thiamin monophosphate from hydroxyethylthiazole |
Saccharomyces cerevisiae |
diphosphate + ? |
- |
? |
2.5.1.3 | 2-methyl-4-amino-5-diphosphomethylpyrimidine + 2-(4-methyl-1,3-thiazol-5-yl)ethyl phosphate |
expression is negatively regulated by thiamin |
Brassica napus |
diphosphate + ? |
- |
? |
2.5.1.3 | 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + (R,Z)-2-(2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate |
- |
Bacillus subtilis |
diphosphate + thiamine phosphate + CO2 |
the enzyme catalyzes the tautomerization and decarboxylation of the intermediate (2R,5Z)-3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-carboxy-4-methyl-5-[2-(phosphonooxy)ethylidene]-2,5-dihydro-1,3-thiazol-3-ium |
? |
2.5.1.3 | 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + (R,Z)-2-(2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate |
- |
Bacillus subtilis 168 |
diphosphate + thiamine phosphate + CO2 |
the enzyme catalyzes the tautomerization and decarboxylation of the intermediate (2R,5Z)-3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-carboxy-4-methyl-5-[2-(phosphonooxy)ethylidene]-2,5-dihydro-1,3-thiazol-3-ium |
? |
2.5.1.3 | 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate |
- |
Bacillus subtilis |
diphosphate + thiamine phosphate + CO2 |
the enzyme catalyzes the decarboxylation of the intermediate 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-carboxy-4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazol-3-ium |
? |
2.5.1.3 | 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate |
- |
Bacillus subtilis 168 |
diphosphate + thiamine phosphate + CO2 |
the enzyme catalyzes the decarboxylation of the intermediate 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-carboxy-4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazol-3-ium |
? |
2.5.1.3 | 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)-thiazole |
- |
Vicia faba |
thiamine monophosphate + diphosphate |
- |
? |
2.5.1.3 | 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)-thiazole |
- |
Bacillus subtilis |
thiamine monophosphate + diphosphate |
- |
? |