EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.316 | tylactone + dTDP-alpha-D-mycaminose |
the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin |
Streptomyces fradiae |
dTDP + 5-O-beta-D-mycaminosyltylactone |
- |
? |
2.4.1.316 | tylactone + dTDP-alpha-D-mycaminose |
the enzyme is flexible toward the acceptor substrate, glycosylating 16-membered tylactone and 12-membered ring macrolide |
Streptomyces fradiae |
dTDP + 5-O-beta-D-mycaminosyltylactone |
- |
? |
2.4.1.316 | tylactone + dTDP-D-desosaminose |
- |
Streptomyces fradiae |
dTDP + 5-O-desosaminyl-tylactone |
- |
? |
2.4.1.316 | tylactone + dTDP-D-mycaminose |
the product of gene tylM2 is the glycosyltansferase that adds mycaminose to the 5-hydroxyl group of tylactone |
Streptomyces fradiae |
dTDP + 5-O-beta-D-mycaminosyltylactone |
- |
? |