EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.253 | more |
flavonoids lacking a substitution at the position ortho- to the 7-OH (chrysin, apigenin, luteolin, quercetin, formononetin and daidzein) do not serve as substrates |
Scutellaria baicalensis |
? |
- |
? |
2.4.1.253 | more |
flavonoids lacking a substitution at the position ortho- to the 7-OH (chrysin, apigenin, luteolin, quercetin, formononetin and daidzein) do not serve as substrates |
Scutellaria baicalensis Georgi |
? |
- |
? |
2.4.1.253 | UDP-D-glucuronate + 4',5,6,7-tetrahydroxyflavone |
i.e. 5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one, i.e. scutellarein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis |
UDP + 4',5,6,7-tetrahydroxyflavone 7-O-beta-D-glucuronate |
i.e. scutellarein 7-O-glucuronide |
? |
2.4.1.253 | UDP-D-glucuronate + 4',5,6,7-tetrahydroxyflavone |
i.e. 5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one, i.e. scutellarein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis Georgi |
UDP + 4',5,6,7-tetrahydroxyflavone 7-O-beta-D-glucuronate |
i.e. scutellarein 7-O-glucuronide |
? |
2.4.1.253 | UDP-D-glucuronate + 5,6,7-trihydroxyflavone |
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis |
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate |
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide |
? |
2.4.1.253 | UDP-D-glucuronate + 5,6,7-trihydroxyflavone |
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis |
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate |
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide. Identification and quantitation of the enzyme reaction products are carried out by reversed phase-HPLC |
? |
2.4.1.253 | UDP-D-glucuronate + 5,6,7-trihydroxyflavone |
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis Georgi |
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate |
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide |
? |
2.4.1.253 | UDP-D-glucuronate + 5,6,7-trihydroxyflavone |
i.e. 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, i.e. baicalein. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis Georgi |
UDP + 5,6,7-trihydroxyflavone-7-O-beta-D-glucuronate |
i.e. 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, i.e. baicalein 7-O-glucuronide. Identification and quantitation of the enzyme reaction products are carried out by reversed phase-HPLC |
? |
2.4.1.253 | UDP-D-glucuronate + 5,7-dihydroxy-8-methoxyflavone |
i.e. 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one, i.e. wogonin. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis |
UDP + 5,7-dihydroxy-8-methoxyflavone-7-O-beta-D-glucuronate |
i.e wogonin 7-O-glucuronide |
? |
2.4.1.253 | UDP-D-glucuronate + 5,7-dihydroxy-8-methoxyflavone |
i.e. 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one, i.e. wogonin. The enzyme is specific to UDP-glucuronic acid as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe) |
Scutellaria baicalensis Georgi |
UDP + 5,7-dihydroxy-8-methoxyflavone-7-O-beta-D-glucuronate |
i.e wogonin 7-O-glucuronide |
? |