EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wg]-L-serine |
- |
Drosophila melanogaster |
CoA + [Wg]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wg]-L-serine |
Wnt substrate from Drosophila melanogaster |
Mus musculus |
CoA + [Wg]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
- |
Gallus gallus |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
- |
Homo sapiens |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
- |
Mus musculus |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
chick WNT1 protein, the enzyme is an O-acyl transferase for WNT1 protein, WNT1 residues 214-234 are sufficient for PORCN-dependent palmitoylation of Ser224. Substitution of Ser224 with Thr, but not Cys, is tolerated in palmitoylation and biological assays. Transiently transfection of HEK-293T cells with WNT1. WNT1 mutant S224T is accepted as substrate, while mutants S224A and S224C are inactive |
Homo sapiens |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
chicken substrate, and chimeric recombinant substrate containing amino acids 1-63 from mouse Wnt1 (-EPSLQL) and amino acids 64-370 from chicken Wnt1 (LSRKQ-) |
Gallus gallus |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
chicken substrate, and chimeric recombinant substrate containing amino acids 1-63 from mouse Wnt1 (-EPSLQL) and amino acids 64-370 from chicken Wnt1 (LSRKQ-) |
Homo sapiens |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt1]-L-serine |
chicken substrate, and chimeric recombinant substrate containing amino acids 1-63 from mouse Wnt1 (-EPSLQL) and amino acids 64-370 from chicken Wnt1 (LSRKQ-) |
Mus musculus |
CoA + [Wnt1]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |
2.3.1.250 | (9Z)-hexadec-9-enoyl-CoA + [Wnt3a]-L-serine |
- |
Gallus gallus |
CoA + [Wnt3a]-O-(9Z)-hexadec-9-enoyl-L-serine |
- |
? |