EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.B83 | 2 S-adenosyl-L-methionine + 7'-O-demethylcephaeline |
the enzyme is involved in biosynthesis of emetine |
Carapichea ipecacuanha |
2 S-adenosyl-L-homocysteine + emetine |
- |
? |
2.1.1.B83 | 2 S-adenosyl-L-methionine + 7'-O-demethylcephaeline |
the enzyme is involved in biosynthesis of emetine. Almost all of the 7'-O-demethylcephaeline is converted to cephaline within 2 min. Emetine the methylation product of cephaline is not observed, which indicates thatCiOMT1 does not use cephaline as a preferred substrate compared to 7'-O-demethylcephaeline. When all of the 7'-O-demethylcephaeline is converted to cephaline after 10 min, emetine is gradually produced from cephaline |
Carapichea ipecacuanha |
2 S-adenosyl-L-homocysteine + emetine |
- |
? |
2.1.1.B83 | S-adenosyl-L-methionine + 7'-O-demethylcephaeline |
- |
Carapichea ipecacuanha |
S-adenosyl-L-homocysteine + cephaeline |
- |
? |
2.1.1.B83 | S-adenosyl-L-methionine + cephaeline |
- |
Carapichea ipecacuanha |
2 S-adenosyl-L-homocysteine + emetine |
- |
? |