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Results 1 - 9 of 9
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.1.1.B1272 S-adenosyl-L-methionine + trans-resveratrol - Acorus calamus 2 S-adenosyl-L-homocysteine + pterostilbene - ?
Display the reaction diagram Show all sequences 2.1.1.B127more recombinant AcOMT1 shows high 4'-O-methylation activity toward resveratrol and its derivative, isorhapontigenin. The reaction product enzymatically formed from resveratrol by AcOMT1 is determined and confirmed as 4'-O-methylresveratrol. Substrate specificity, overview. Activity of AcOMT1 is the greatest toward isorhapontigenin, followed by resveratrol. Recombinant AcOMT1 exhibits lower activity toward other resveratrol derivatives, piceatannol, oxyresveratrol, and pinostilbene (with 9-24% of the activity observed with resveratrol), and no activity toward pterostilbene or pinosylvin. AcOMT1 shows high 4'-O-methylation activity toward stilbenes with non-methylated phloroglucinol rings. the enzyme shows very low activity with isoeugenol, chavicol, eugenol, 4-coumaric acid, and caffeic acid (below 5% of the activity with resveratrol). Reaction products are analyzed using GC-MS Acorus calamus ? - -
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + cyclohexanol moderate activity Acorus calamus S-adenosyl-L-homocysteine + 4-methoxycyclohexanol - ?
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + isorhapontigenin i.e. 5-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]benzene-1,3-diol, best substrate Acorus calamus S-adenosyl-L-homocysteine + 4'-O-methylisorhapontigenin - ?
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + naringenin moderate activity Acorus calamus S-adenosyl-L-homocysteine + 4'-O-methylnaringenin - ?
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + oxyresveratrol i.e. 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol, low activity Acorus calamus S-adenosyl-L-homocysteine + 4'-O-methyloxyresveratrol - ?
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + piceatannol i.e. 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol, moderate activity Acorus calamus S-adenosyl-L-homocysteine + 4'-O-methylpiceatannol - ?
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + pinostilbene i.e. 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenol, low activity Acorus calamus S-adenosyl-L-homocysteine + 4'-O-methylpinostilbene - ?
Display the reaction diagram Show all sequences 2.1.1.B127S-adenosyl-L-methionine + resveratrol i.e. 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol, high activity Acorus calamus S-adenosyl-L-homocysteine + 4'-O-methylresveratrol - ?
Results 1 - 9 of 9
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