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Results 1 - 10 of 19 > >>
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.1.1.88more not: glycosides of 8-hydroxyflavonols Lotus corniculatus ? - ?
Display the reaction diagram Show all sequences 2.1.1.88more the enzyme shows a broad substrate specificity. SpOMT7740 catalyzes the O-methylation reaction to form various natural and non-natural O-methoxides, includes 7-hydroxy-8-O-methoxy flavone, 3-O-methoxy flavone, three mono-, di-, and tri-O-methoxy genistein, mono-O-methoxy phloretin, mono-O-methoxy luteolin, 3-O-methoxy beta-sitosterol, and O-methoxy anthraquinones (emodin and aloe emodin) and O-methoxy anthracycline (daunorubicin) exhibiting diverse substrate flexibility. Mass spectrometric analysis of reaction products. 7,8-Dihydroxyflavone is the best substrate for bioconversion to 7-hydroxy-8-O-methoxy flavone. The enzyme seems to prefer methylation of hydroxy groups at C8 position. No or poor activity with doxorubicin and daunorubicin Streptomyces peucetius subsp. caesius ? - -
Display the reaction diagram Show all sequences 2.1.1.88more the enzyme shows a broad substrate specificity. SpOMT7740 catalyzes the O-methylation reaction to form various natural and non-natural O-methoxides, includes 7-hydroxy-8-O-methoxy flavone, 3-O-methoxy flavone, three mono-, di-, and tri-O-methoxy genistein, mono-O-methoxy phloretin, mono-O-methoxy luteolin, 3-O-methoxy beta-sitosterol, and O-methoxy anthraquinones (emodin and aloe emodin) and O-methoxy anthracycline (daunorubicin) exhibiting diverse substrate flexibility. Mass spectrometric analysis of reaction products. 7,8-Dihydroxyflavone is the best substrate for bioconversion to 7-hydroxy-8-O-methoxy flavone. The enzyme seems to prefer methylation of hydroxy groups at C8 position. No or poor activity with doxorubicin and daunorubicin Streptomyces peucetius subsp. caesius ATCC 27952 ? - -
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 3,3',4',5,7,8-hexahydroxyflavone - Lotus corniculatus S-adenosyl-L-homocysteine + 3,3',4',5,7-pentahydroxy-8-methoxyflavone - ?
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 3,3',4',5,7,8-hexahydroxyflavone i.e. 8-hydroxyquercetin Lotus corniculatus S-adenosyl-L-homocysteine + 3,3',4',5,7-pentahydroxy-8-methoxyflavone i.e. 8-methoxyquercetin ?
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 3,5,7,8,3',4'-hexahydroxyflavone - Streptomyces peucetius subsp. caesius S-adenosyl-L-homocysteine + 3,5,7,3',4'-pentahydroxy-8-methoxyflavone - ?
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 3,5,7,8,3',4'-hexahydroxyflavone - Streptomyces peucetius subsp. caesius ATCC 27952 S-adenosyl-L-homocysteine + 3,5,7,3',4'-pentahydroxy-8-methoxyflavone - ?
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 3-hydroxyflavone lower activity Streptomyces peucetius subsp. caesius S-adenosyl-L-homocysteine + 3-methoxyflavone - ?
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 3-hydroxyflavone lower activity Streptomyces peucetius subsp. caesius ATCC 27952 S-adenosyl-L-homocysteine + 3-methoxyflavone - ?
Display the reaction diagram Show all sequences 2.1.1.88S-adenosyl-L-methionine + 7,8-dihydroxyflavone best substrate Streptomyces peucetius subsp. caesius S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxyflavone - ?
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