EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2 |
- |
Thermotoga maritima |
tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2 |
TrmFO is a methyltransferase that catalyzes the formation of 5-methyluridine or ribothymidine at position 54 in tRNA in some Gram-positive bacteria |
Thermotoga maritima |
tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2 |
tetrahydrofolate is sandwiched between the flavin ring of FAD and the imidazole ring of a His residue, the transferring methylene group of MTHF is located close to the redox-active N5 atom of FAD, TrmFO-tRNA docking model and active site structure, overview |
Thermotoga maritima |
tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Bacillus subtilis |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Geobacillus stearothermophilus |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Enterococcus faecalis |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Bacillus cereus |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Mycobacterium leprae |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Mycobacterium tuberculosis |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |
2.1.1.74 | 5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2 |
- |
Clostridium acidi-urici |
tetrahydrofolate + tRNA TpsiC + FAD |
- |
? |