EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + 3-mercaptopropanoic acid |
- |
Methanosarcina barkeri |
methyl-3-mercaptopropanoic acid + a [Co(I) methanol-specific corrinoid protein] |
- |
r |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M |
- |
Methanosarcina barkeri |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
? |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M |
- |
Methanosarcina barkeri |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
r |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M |
the enzyme methylcobamide:CoM methyltransferase, MT2, catalyzes the transfer of the methyl group from the MT1-bound methylcobamide prosthetic group to coenzyme M |
Methanosarcina barkeri |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
r |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M |
- |
Methanosarcina barkeri Fusaro, DSM 804 |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
r |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M |
- |
Methanosarcina barkeri Fusaro / DSM 804 |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
r |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + CoM |
- |
Methanosarcina barkeri |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
? |
2.1.1.246 | a [methyl-Co(III) methanol-specific corrinoid protein] + CoM |
- |
Methanosarcina barkeri |
methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
- |
r |
2.1.1.246 | more |
transferase MtaA catalyzes the transfer of the methyl group from methylated transferase MtaBC to coenzyme M. Instead of methylated transferase MtaBC, MtaA can also use free methylcobalamin as the methyl donor. MtaA activates coenzyme M for nucleophilic attack of the methyl group of the methylcobamide |
Methanosarcina barkeri |
? |
- |
? |
2.1.1.246 | more |
conversions of monomethylamine and dimethylamine to CH3-SCoM are dependent upon MT2-A, and are not supported by MT2-M. In contrast, MT2-M acts specifically in metabolism of methanol, but does not substitute for MT2-A in conversion of monomethylamine or dimethylamine. Nevertheless, both isozymes are capable of supporting the conversion of trimethylamine |
Methanosarcina barkeri |
? |
- |
? |