EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.239 | more |
no bioconversion is observed when other glycosylated macrolide antibiotics (spiramycin, niddamycin, carbomycin) are added to cultures of Streptomyces albus NAG2(pLR14b-4). These three macrolides contain L-mycarose moieties with a free 3-hydroxy group but are not methylated by OleY |
Streptomyces antibioticus |
? |
- |
? |
2.1.1.239 | S-adenosyl-L-methionine + L-mycarosyl-erythronolide B |
poor substrate |
Streptomyces antibioticus |
S-adenosyl-L-homocysteine + ? |
- |
? |
2.1.1.239 | S-adenosyl-L-methionine + L-olivosyl-erythronolide B |
- |
Streptomyces antibioticus |
S-adenosyl-L-homocysteine + L-oleandrosyl-erythronolide B |
- |
? |
2.1.1.239 | S-adenosyl-L-methionine + L-olivosyl-erythronolide B |
the enzyme is involved in biosynthesis of the macrolide antibiotic oleandomycin |
Streptomyces antibioticus |
S-adenosyl-L-homocysteine + L-oleandrosyl-erythronolide B |
- |
? |
2.1.1.239 | S-adenosyl-L-methionine + L-rhamnosyl-erythronolide B |
- |
Streptomyces antibioticus |
S-adenosyl-L-homocysteine + ? |
- |
? |