EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    2.1.1.20 | more |
all-trans-retinoic acid and dexamethasone independently induce GNMT in liver, no effect on enzyme from pancreas |
Rattus norvegicus |
? |
- |
? |
| 2.1.1.20 | more |
interaction of benzo(a)pyrene with the enzyme may contribute to carcinogenesis |
Homo sapiens |
? |
- |
? |
| 2.1.1.20 | more |
major folate binding protein |
Mus musculus |
? |
- |
? |
| 2.1.1.20 | more |
major folate binding protein |
Homo sapiens |
? |
- |
? |
| 2.1.1.20 | more |
major folate binding protein |
Rattus norvegicus |
? |
- |
? |
| 2.1.1.20 | more |
major folate binding protein, interacts with environmental carcinogens such as benzo(a)pyrene |
Homo sapiens |
? |
- |
? |
| 2.1.1.20 | more |
major folate binding protein, involved in the regulation of the expression of S-adenosylhomocysteine hydrolase and formiminotransferase cyclodeaminase, binds benzo(a)pyrene and prevents DNA-adduct formation |
Mus musculus |
? |
- |
? |
| 2.1.1.20 | more |
GNMT is phosphorylated by cAMP-dependent protein kinase at Ser9, Ser71, Ser139, Ser182, and Ser241 |
Mus musculus |
? |
- |
? |
| 2.1.1.20 | more |
a mammalian target of rapamycin (mTOR) inhibitor (DEP domain containing MTOR-interacting protein [DEPDC6/DEPTOR]) is identified as a GNMT-binding protein by using yeast two-hybrid screening. The C-terminal half of GNMT interacts with the PSD-95/Dlg1/ZO-1 (PDZ) domain of DEPDC6/DEPTOR |
Homo sapiens |
? |
- |
? |
| 2.1.1.20 | more |
kinetic isotope effects at the transferred methyl group implicate a compaction effect that is conferred by the protein structure |
Rattus norvegicus |
? |
- |
- |
