EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.155 | more |
the role of F 4-OMT is mainly defensive against parasites, rather than structural |
Dianthus caryophyllus |
? |
- |
? |
2.1.1.155 | more |
not: 4-hydroxybenzoic acid, gallic acid, p-coumaric acid, caffeic acid, caffeoyl-CoA, quercetin, rutin, luteolin, eriodictyol, 3,4,7-trihydroxyisoflavone, datiscetin |
Dianthus caryophyllus |
? |
- |
? |
2.1.1.155 | more |
not: naringenin, pentahydroxyflavanone, hesperetin, myricetin, 7,3-O-dimethylquercetin, 7-O-methylquercetin, syringetin, apigenin, luteolin, tricetin, velutin, dihydrokaempferol, dihydroquercetin, dihydromyricetin, 3-O-methyl-dihydroquercetin |
Catharanthus roseus |
? |
- |
? |
2.1.1.155 | S-adenosyl-L-methionine + 4'-hydroxyflavanone |
- |
Dianthus caryophyllus |
S-adenosyl-L-homocysteine + 4'-methoxyflavanone |
- |
? |
2.1.1.155 | S-adenosyl-L-methionine + a flavonoid |
4-OMT methylates the position 4 in the B-ring of flavonoids, uses flavonoids methylated in the 3-position of the B-ring to synthesize a 3,4-methylated product, a methylated flavanone, homoeriodictyol, is the best substrate |
Catharanthus roseus |
S-adenosyl-L-homocysteine + a 4'-methoxyflavonoid |
- |
? |
2.1.1.155 | S-adenosyl-L-methionine + a flavonoid |
F 4-OMT specifically methylates the hydroxy substituent in 4-position of the flavones, flavanones and isoflavones in the presence of S-adenosyl-L-methionine, enzyme affinity for the substrate and catalytic efficiency decreases in the following order: 4-hydroxyflavones, 4-hydroxyflavanones, 4-hydroxyisoflavones, ping-pong mechanism, which excludes the formation of a ternary complex |
Dianthus caryophyllus |
S-adenosyl-L-homocysteine + a 4'-methoxyflavonoid |
- |
? |
2.1.1.155 | S-adenosyl-L-methionine + apigenin |
- |
Dianthus caryophyllus |
S-adenosyl-L-homocysteine + acacetin |
4-methoxyapigenin |
? |
2.1.1.155 | S-adenosyl-L-methionine + chrysoeriol |
good substrate |
Catharanthus roseus |
S-adenosyl-L-homocysteine + 4'-methoxychrysoeriol |
- |
? |
2.1.1.155 | S-adenosyl-L-methionine + eriodictyol |
lower activity than with homoeriodictyol, isorhamnetin or chrysoeriol |
Catharanthus roseus |
S-adenosyl-L-homocysteine + 4'-methoxyeriodictyol |
- |
? |
2.1.1.155 | S-adenosyl-L-methionine + genistein |
- |
Dianthus caryophyllus |
S-adenosyl-L-homocysteine + biochanin A |
4-methoxygenistein |
? |