EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.2.7.3 | 2-oxoglutarate + CoA + 2 oxidized ferredoxin |
- |
Magnetococcus marinus |
succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ |
- |
r |
1.2.7.3 | 2-oxoglutarate + CoA + 2 oxidized ferredoxin |
specific for 2-oxoglutarate |
Thauera aromatica |
succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + 2 oxidized ferredoxin |
pure enzyme does not utilize other 2-keto acids, such as pyruvate, phenylglyoxylate, indolepyruvate, 2-oxobutanoate or 2-oxoisovalerate, as substrates |
Thermococcus litoralis |
succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + 2 oxidized ferredoxin |
pure enzyme does not utilize other 2-keto acids, such as pyruvate, phenylglyoxylate, indolepyruvate, 2-oxobutanoate or 2-oxoisovalerate, as substrates |
Thermococcus litoralis DSM 5473 |
succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + 2 oxidized ferredoxin |
- |
Magnetococcus marinus MC-1 |
succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+ |
- |
r |
1.2.7.3 | 2-oxoglutarate + CoA + oxidized ferredoxin |
- |
Hydrogenobacter thermophilus |
succinyl-CoA + CO2 + reduced ferredoxin |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + oxidized ferredoxin |
involved in carbon dioxide fixation via a reductive TCA cycle |
Hydrogenobacter thermophilus |
succinyl-CoA + CO2 + reduced ferredoxin |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + oxidized ferredoxin |
involved in reductive TCA cycle |
Hydrogenobacter thermophilus |
succinyl-CoA + CO2 + reduced ferredoxin |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + oxidized ferredoxin |
one of the key enzymes of the reductive TCA cycle. The physiological function is the reductive carboxylation of succinyl-CoA to produce 2-oxoglutarate, growth under aerobic conditions. Under anaerobic conditions only the Kor enzyme is expressed. The enzyme For supports the optimal growth of the organism in the presence of oxygen |
Hydrogenobacter thermophilus |
succinyl-CoA + CO2 + reduced ferredoxin |
- |
? |
1.2.7.3 | 2-oxoglutarate + CoA + oxidized ferredoxin |
activity of the recombinant enzyme with 2-oxobutyrate, 2-oxoisocaproate, 2-oxoisovalerate, oxalacetate, oxomalonate, pyruvate or phosphoenolpyruvate is less than 5% of the activity with 2-oxoglutarate |
Hydrogenobacter thermophilus |
succinyl-CoA + CO2 + reduced ferredoxin |
- |
? |