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Results 1 - 10 of 17 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11(R)-nicotine + O2 + [reduced NADPH-hemoprotein reductase] + O2 isoforms CYP82E4, CYP82E5v2, and CYP82E10 demethylate (R)-nicotine 3, 10, and 10fold faster than (S)-nicotine, respectively Nicotiana tabacum (R)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11(S)-nicotine + [reduced NADPH-hemoprotein reductase] + O2 - Nicotiana alata (S)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11(S)-nicotine + [reduced NADPH-hemoprotein reductase] + O2 - Nicotiana langsdorffii (S)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11(S)-nicotine + [reduced NADPH-hemoprotein reductase] + O2 CYP82E4 selectively demethylates (S)-nicotine Nicotiana tabacum (S)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11(S)-nicotine + [reduced NADPH-hemoprotein reductase] + O2 only isoform CYP82E4 can significantly convert (S)-nicotine to (S)-nornicotine Nicotiana tabacum (S)-nornicotine + formaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11more isoforms CYP2A6 and CYP2B6 significantly contribute to the nicotine N-demethylation at low and high substrate concentrations, respectively Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11nicotine + NADPH + H+ - Nicotiana tabacum nornicotine + NADP+ - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11nicotine + NADPH + O2 + H+ - Nicotiana tabacum nornicotine + formaldehyde + NADP+ + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11nicotine + NADPH + O2 + H+ demethylates nicotine to form nornicotine, a precursor to the nitrosamine N'-nitrosonornicotine Nicotiana tabacum nornicotine + formaldehyde + NADP+ + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11nicotine + NADPH + O2 + H+ six putative substrate recognition sites Nicotiana tabacum nornicotine + formaldehyde + NADP+ + H2O - ?
Results 1 - 10 of 17 > >>