EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.105 | cytochrome c + FAD + FMN + O2 |
rat cytochrome b5 |
Taxus cuspidata |
? |
- |
? |
1.14.14.105 | more |
catalyzes early step in taxol biosynthesis |
Taxus sp. |
? |
- |
? |
1.14.14.105 | taxa-4(20),11(12)-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus x media |
taxa-4(20),11(12)-dien-5alpha-yl acetyl-10beta-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.105 | taxa-4(20),11(12)-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus sp. |
taxa-4(20),11(12)-dien-5alpha-yl acetyl-10beta-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
product identification and quantification by HPLC and GC-MS |
? |
1.14.14.105 | taxa-4(20),11(12)-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
second P450-dependent step in taxol biosynthesis, regulation mechanism involving elicitors |
Taxus x media |
taxa-4(20),11(12)-dien-5alpha-yl acetyl-10beta-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.105 | taxa-4(20),11(12)-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
step in taxol biosynthesis, metabolite analysis and pathway overview |
Taxus sp. |
taxa-4(20),11(12)-dien-5alpha-yl acetyl-10beta-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.105 | taxa-4(20),11-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus sp. |
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.105 | taxadien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus cuspidata |
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.105 | taxadien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme is involved in the taxol biosynthetic pathway, overview |
Taxus cuspidata |
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |