EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.13.215 | protoasukamycin + NADH + H+ + O2 |
- |
Streptomyces nodosus |
4-hydroxyprotoasukamycin + NAD+ + H2O |
- |
? |
1.14.13.215 | protoasukamycin + NADH + H+ + O2 |
enzyme AsuE1 is a flavin-dependent protoasukamycin hydroxylase, that belongs to the family of single-component monooxygenases: a single enzyme catalyzes both the reduction of flavin by NADPH, and the hydroxylation using molecular oxygen and reduced flavin cofactor |
Streptomyces nodosus |
4-hydroxyprotoasukamycin + NAD+ + H2O |
- |
? |
1.14.13.215 | protoasukamycin + NADH + H+ + O2 |
NADH is the preferred cofactor, it reduces the flavin that gets oxidized in the hydroxylation of protoasukamycin, reaction chain overview |
Streptomyces nodosus |
4-hydroxyprotoasukamycin + NAD+ + H2O |
- |
? |
1.14.13.215 | protoasukamycin + NADH + H+ + O2 |
enzyme AsuE1 is a flavin-dependent protoasukamycin hydroxylase, that belongs to the family of single-component monooxygenases: a single enzyme catalyzes both the reduction of flavin by NADPH, and the hydroxylation using molecular oxygen and reduced flavin cofactor |
Streptomyces nodosus ATCC 29757 |
4-hydroxyprotoasukamycin + NAD+ + H2O |
- |
? |
1.14.13.215 | protoasukamycin + NADH + H+ + O2 |
NADH is the preferred cofactor, it reduces the flavin that gets oxidized in the hydroxylation of protoasukamycin, reaction chain overview |
Streptomyces nodosus ATCC 29757 |
4-hydroxyprotoasukamycin + NAD+ + H2O |
- |
? |
1.14.13.215 | protoasukamycin + NADPH + H+ + O2 |
- |
Streptomyces nodosus |
4-hydroxyprotoasukamycin + NADP+ + H2O |
- |
? |
1.14.13.215 | protoasukamycin + NADPH + H+ + O2 |
- |
Streptomyces nodosus ATCC 29757 |
4-hydroxyprotoasukamycin + NADP+ + H2O |
- |
? |