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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20more prostaglandin D2 and prostaglandin E2 are not reduced Mus musculus ? - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20more neither prostaglandin E2 nor prostamide D2 serve as a substrate even at the concentration of 1.5 mM Mus musculus ? - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20more the recombinant enzyme requires thioredoxin as a reducing equivalent donor more efficiently than NADPH, NADH, or GSH Mus musculus ? - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20prostaglandin H2 + reduced thioredoxin - Mus musculus prostaglandin F2alpha + oxidized thioredoxin - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20prostamide F2alpha + oxidized thioredoxin - Mus musculus prostamide H2 + reduced thioredoxin - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20prostamide H2 + reduced thioredoxin - Mus musculus prostamide F2alpha + oxidized thioredoxin - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20prostamide H2 + reduced thioredoxin - Rattus norvegicus prostamide F2alpha + oxidized thioredoxin - ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20thioredoxin + (5Z)-N-(2-hydroxyethyl)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide (5Z)-N-(2-hydroxyethyl)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide i.e. prostamide H2. The product of the reaction prostamide F2alpha is a COX-2-catalyzed metabolite of arachidonoyl ethanolamide that induces important pharmacological actions via interaction with a putative prostamide receptor Mus musculus thioredoxin disulfide + (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide i.e. prostamide F2alpha ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20thioredoxin + (5Z)-N-(2-hydroxyethyl)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide (5Z)-N-(2-hydroxyethyl)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide i.e. prostamide H2 Sus scrofa thioredoxin disulfide + (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide i.e. prostamide F2alpha ?
Show all pathways known for 1.11.1.20Display the reaction diagram Show all sequences 1.11.1.20thioredoxin + (5Z)-N-(2-hydroxyethyl)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide (5Z)-N-(2-hydroxyethyl)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide i.e. prostamide H2. Prostaglandin H2 and prostamide H2 are the best substrates Mus musculus thioredoxin disulfide + (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide i.e. prostamide F2alpha ?
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