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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.1.1.345
(R)-2-hydroxy-4-methylpentanoate + NAD+
i.e. (R)-2-hydroxyisocaproate
Lacticaseibacillus casei
4-methyl-2-oxopentanoate + NADH + H+
i.e. 2-oxoisocaproate
r
1.1.1.345
(R)-2-hydroxycarboxylate + NAD+
-
Lactobacillus delbrueckii subsp. bulgaricus
a 2-oxocarboxylate + NADH + H+
-
r
1.1.1.345
(R)-2-hydroxycarboxylate + NAD+
-
Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842
a 2-oxocarboxylate + NADH + H+
-
r
1.1.1.345
(R)-mandelate + NAD+
Vmax/Km is 0.4% compared to 4-methyl-2-oxopentanoate
Enterococcus faecalis
phenylglyoxylate + NADH + H+
-
?
1.1.1.345
(R)-mandelate + NAD+
Vmax/Km is 1% compared to 4-methyl-2-oxopentanoate
Enterococcus faecalis
phenylglyoxylate + NADH + H+
-
?
1.1.1.345
(R)-mandelate + NAD+
Vmax/KM is less than 1% compared to 4-methyl-2-oxopentanoate
Enterococcus faecalis
phenylglyoxylate + NADH + H+
-
?
1.1.1.345
2-formylbutanethioate + NADH + H+
i.e. 2-ketomethylthiobutyrate
Lactococcus cremoris
?
-
?
1.1.1.345
2-formylbutanethioate + NADH + H+
i.e. 2-ketomethylthiobutyrate
Lactococcus cremoris TIL46
?
-
?
1.1.1.345
2-hydroxyhexanoate + NAD+
-
Lacticaseibacillus casei
2-oxohexanoate + NADH + H+
-
r
1.1.1.345
2-hydroxyoctanoate + NAD+
-
Lacticaseibacillus casei
2-oxooctanoate + NADH + H+
-
r
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