EC Number   |
Substrates   |
Products   |
Reversibility   |
|---|
6.2.1.76 | ATP + 2-methylmalonate + CoA |
activity is 53.6% compared to the activity with malonate |
AMP + diphosphate + 2-methyl-malonyl-CoA |
- |
? |
6.2.1.76 | ATP + 2-methylmalonate + CoA |
activity is 20.4% compared to the activity with malonate |
AMP + diphosphate + 2-methylmalonyl-CoA |
- |
? |
6.2.1.76 | ATP + 2-methylmalonate + CoA |
activity with 2-methylmalonate is 12% compared to the activity malonate |
AMP + diphosphate + 2-methylmalonyl-CoA |
- |
? |
6.2.1.76 | ATP + malonate + CoA |
- |
AMP + diphosphate + malonyl-CoA |
- |
? |
6.2.1.76 | ATP + malonate + CoA |
high substrate specificity on malonate and ATP |
AMP + diphosphate + malonyl-CoA |
- |
? |
6.2.1.76 | ATP + malonate + CoA |
ordered bi uni uni bi ping pong ter ter mechanism |
AMP + diphosphate + malonyl-CoA |
- |
? |
6.2.1.76 | ATP + malonate + CoA |
with activity with acetate, propionate, or succinate in place of malonate, or with GTP or CTP in place of ATP |
AMP + diphosphate + malonyl-CoA |
- |
? |
6.2.1.76 | ATP + malonate + CoA |
no activity with oxalate, succinate, butyrate, octanoate, laurate, palmitate, oleate, or lignocerate |
AMP + diphosphate + malonyl-CoA |
- |
? |
6.2.1.76 | ATP + malonate + CoA |
little or no activity against other dicarboxylic or fatty acids |
AMP + diphosphate + malonyl-CoA |
- |
? |
6.2.1.76 | ATP + methylmalonate + CoA |
the kcat/KM value for methylmalonate is 12.6fold lower than the kcat/Km value for malonate |
AMP + diphosphate + methylmalonyl-CoA |
- |
? |