EC Number   |
Substrates |
Products |
Reversibility |
|---|
  6.2.1.43 | ATP + 1-naphthoate + CoA |
kcat/Km is 0.6% compared to the wild-type value |
AMP + diphosphate + 1-naphthoyl-CoA |
- |
? |
| 6.2.1.43 | ATP + 2,7-dihydroxy-5-methyl-1-naphthoate + CoA |
kcat/Km is 47% compared to the wild-type value |
AMP + diphosphate + 2,7-dihydroxy-5-methyl-1-naphthoyl-CoA |
- |
? |
| 6.2.1.43 | ATP + 2,7-dihydroxy-5-methylnaphthalene-1-carboxylic acid + CoA |
47% activity compared to 2-hydroxy-7-methoxy-5-methyl-1-naphthoate |
AMP + diphosphate + ? |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-1-naphthoate + CoA |
kcat/Km is 1.3% compared to the wild-type value |
AMP + diphosphate + 2-hydroxy-1-naphthoyl-CoA |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-5,7-dimethoxy-1-naphthoate + CoA |
kcat/Km is 35% compared to the wild-type value |
AMP + diphosphate + 2-hydroxy-5,7-dimethoxy-1-naphthoyl-CoA |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-5,7-dimethoxynaphthalene-1-carboxylic acid + CoA |
35% activity compared to 2-hydroxy-7-methoxy-5-methyl-1-naphthoate |
AMP + diphosphate + ? |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-5-methyl-1-naphthoate + CoA |
kcat/Km is 50% compared to the wild-type value |
AMP + diphosphate + 2-hydroxy-5-methyl-1-naphthoyl-CoA |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-5-methylnaphthalene-1-carboxylic acid + CoA |
50% activity compared to 2-hydroxy-7-methoxy-5-methyl-1-naphthoate |
AMP + diphosphate + ? |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-7-methoxy-1-naphthoate + CoA |
kcat/Km is 5% compared to the wild-type value |
AMP + diphosphate + 2-hydroxy-7-methoxy-1-naphthoyl-CoA |
- |
? |
| 6.2.1.43 | ATP + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA |
the enzyme is involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin |
AMP + diphosphate + 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA |
- |
? |
