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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64(S)-3-hydroxybutanoyl-CoA - Aquincola tertiaricarbonis 2-hydroxy-2-methylpropanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64(S)-3-hydroxybutanoyl-CoA - Aquincola tertiaricarbonis L108 2-hydroxy-2-methylpropanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.642-hydroxy-2-methylpropanoyl-CoA - Aquincola tertiaricarbonis (S)-3-hydroxybutanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.642-hydroxyisobutanoyl-CoA - Kyrpidia tusciae DSM 2912 (S)-3-hydroxyisobutanoyl-CoA + (R)-3-hydroxyisobutanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64isobutanoyl-CoA - Aquincola tertiaricarbonis butanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64methylmalonyl-CoA - Aquincola tertiaricarbonis succinyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64more (R)-3-hydroxybuytryl-CoA is converted 3.1 times faster than the (S)-enantiomer Kyrpidia tusciae DSM 2912 ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64(R)-3-hydroxybutanoyl-CoA 2-hydroxy-2-methylpropanoyl i.e. 2-hydroxyisobutanoyl-CoA. 2-Hydroxyisobutanoyl-CoA is predominantly converted to (S)-3-hydroxybutanoyl-CoA, and only minor amounts of about 20% of the (R)-enantiomer are obtained Aquincola tertiaricarbonis 2-hydroxy-2-methylpropanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.64(R)-3-hydroxybutanoyl-CoA 2-hydroxy-2-methylpropanoyl i.e. 2-hydroxyisobutanoyl-CoA. 2-Hydroxyisobutanoyl-CoA is predominantly converted to (S)-3-hydroxybutanoyl-CoA, and only minor amounts of about 20% of the (R)-enantiomer are obtained Aquincola tertiaricarbonis L108 2-hydroxy-2-methylpropanoyl-CoA - r
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.642-hydroxy-2-methylpropanoyl-CoA 2-hydroxy-2-methylpropanoyl i.e. 2-hydroxyisobutanoyl-CoA. 2-Hydroxyisobutanoyl-CoA is predominantly converted to (S)-3-hydroxybutanoyl-CoA, and only minor amounts of about 20% of the (R)-enantiomer are obtained, indicating stereospecific catalysis. The enzyme uses radical chemistry to rearrange the positions of both a methyl group and a hydroxyl group. Compared with Vmax obtained with 2-hydroxyisobutanoyl-CoA, rates with (S)-3-hydroxybutanoyl-CoA are nearly four times higher Aquincola tertiaricarbonis (S)-3-hydroxybutanoyl-CoA - r
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