EC Number   |
Substrates  |
Organism |
Products |
Reversibility |
|---|
    5.1.3.14 | dihydropyrimidine-2,4(1H,3H)-dione-alpha-D-ribofuranosyl-5'-diphospho-2-acetamido-2-deoxy-alpha-D-mannopyranoside |
- |
Neisseria meningitidis serogroup A / serotype 4A |
? |
- |
? |
| 5.1.3.14 | dihydropyrimidine-2,4(1H,3H)-dione-alpha-D-ribofuranosyl-5'-diphospho-2-acetamido-2-deoxy-alpha-D-mannopyranoside |
- |
Neisseria meningitidis serogroup A / serotype 4A Z2491 |
? |
- |
? |
| 5.1.3.14 | more |
3'-deoxy-UDP-N-acetylglucosamine is not a substrate |
Escherichia coli |
? |
- |
? |
| 5.1.3.14 | more |
bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase |
Rattus norvegicus |
? |
- |
? |
| 5.1.3.14 | more |
enzyme catalyzes the first step in synthesis of sialic acids |
Rattus norvegicus |
? |
- |
? |
| 5.1.3.14 | more |
reaction mechanism involving an anti-elimination of UDP to give 2-acetamidoglucal, followed by a syn-addition of water |
Rattus norvegicus |
? |
- |
? |
| 5.1.3.14 | more |
key enzyme for biosynthesis of N-acetylneuraminate is the bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, catalyzing the first two steps of the biosynthesis in the cytosol |
Homo sapiens |
? |
- |
? |
| 5.1.3.14 | more |
key enzyme of N-acetylneuraminic acid biosynthesis |
Rattus norvegicus |
? |
- |
? |
| 5.1.3.14 | more |
rate-limiting step in sialic acid biosynthesis pathway. The enzyme is the major determinant of cell surface sialylation in hematopoietic cell lines and is a critical regulator of the function of specific cell surface adhesion molecules |
Homo sapiens |
? |
- |
? |
| 5.1.3.14 | more |
the bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/ManNAc kinase catalyzes the first two steps in the biosynthesis of the sialic acids |
Rattus norvegicus |
? |
- |
? |
