EC Number   |
Substrates |
Organism |
Products  |
Reversibility |
|---|
   4.1.2.52 | 2-oxo-3-methyl-4-hydroxypentanoate |
efficient substrate |
Escherichia coli |
2-oxobutyrate + acetaldehyde |
- |
? |
| 4.1.2.52 | pyruvate + succinic semialdehyde |
- |
Escherichia coli |
4-hydroxy-2-oxo-1,7-heptanedioate |
enzyme lacks stereospecific control producing racemic mixtures of its physiological substrate, 4-hydroxy-2-oxo-1,7-heptanedioate |
? |
| 4.1.2.52 | pyruvate + acetaldehyde |
- |
Escherichia coli |
4-hydroxy-2-oxopentanoate |
enzyme lacks stereospecific control producing racemic mixtures of 4-hydroxy-2-oxopentanoate i.e. HOPA |
? |
| 4.1.2.52 | (S)-4-hydroxy-2-oxopentanoate |
- |
Escherichia coli |
? |
- |
? |
| 4.1.2.52 | 2-oxobutanoate + acetaldehyde |
- |
Escherichia coli |
? |
- |
? |
| 4.1.2.52 | 3-deoxy-D-manno-oct-2-ulosonic acid |
3-deoxy-D-manno-oct-2-ulosonic acid i.e. KDO |
Escherichia coli |
? |
- |
? |
| 4.1.2.52 | 4-hydroxy-2-oxohexanoate |
- |
Escherichia coli |
? |
- |
? |
| 4.1.2.52 | 4-hydroxy-2-oxopentanoate |
- |
Escherichia coli |
? |
- |
? |
| 4.1.2.52 | more |
the enzyme exhibits significant oxaloacetate decarboxylase activity, with a kcat value 2.4fold higher than the corresponding value for the aldol cleavage of 4-hydroxy-2-oxopentanoate |
Escherichia coli |
? |
- |
? |
| 4.1.2.52 | pyruvate + butyraldehyde |
- |
Escherichia coli |
? |
- |
? |
