EC Number   |
Substrates |
Products |
Reversibility |
|---|
   3.5.5.5 | (2-bromophenyl)(hydroxy)acetonitrile + H2O |
74% activity compared to phenylacetonitrile |
(2R)-(2-bromophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (2-fluorophenyl)(hydroxy)acetonitrile + H2O |
439% activity compared to phenylacetonitrile |
(2R)-(2-fluorophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (3-bromophenyl)(hydroxy)acetonitrile + H2O |
706% activity compared to phenylacetonitrile |
(2R)-(3-bromophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (3-chlorophenyl)(hydroxy)acetonitrile + H2O |
810% activity compared to phenylacetonitrile |
(2R)-(3-chlorophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (3-fluorophenyl)(hydroxy)acetonitrile + H2O |
454% activity compared to phenylacetonitrile |
(2R)-(3-fluorophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (4-bromophenyl)(hydroxy)acetonitrile + H2O |
680% activity compared to phenylacetonitrile |
(2R)-(4-bromophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (4-chlorophenyl)(hydroxy)acetonitrile + H2O |
1083% activity compared to phenylacetonitrile |
(2R)-(4-chlorophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (4-fluorophenyl)(hydroxy)acetonitrile + H2O |
891% activity compared to phenylacetonitrile |
(2R)-(4-fluorophenyl)(hydroxy)acetic acid + NH3 |
- |
? |
| 3.5.5.5 | (R,S)-2-phenylpropionitrile + 2 H2O |
- |
(S)-2-phenylpropionic acid + NH3 |
ee 66% |
? |
| 3.5.5.5 | (R,S)-2-phenylpropionitrile + 2 H2O |
the enzyme exhibits a low degree of enantioselectivity toward this substrate (e.e. 35% for the (R)-acid at 35% conversion) |
2-phenylpropionic acid + NH3 |
- |
? |
