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Enzyme, Ligand
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EC Number
Substrates
Commentary Substrates
Products
Commentary (Products)
Reversibility
3.4.22.64
caspase-1 + H2O
-
?
-
?
3.4.22.64
cationic channel subunit transient receptor potential channel 1 + H2O
i.e. TRPC1, plays a role in regulating innate immunity by modulating channel complexes during inflammatory responses
?
-
?
3.4.22.64
cationic channel subunit transient receptor potential channel 1 + H2O
-
?
-
?
3.4.22.64
DABYL-GQLSLLSDGID-Glu + H2O
synthetic substrate
?
-
?
3.4.22.64
gasdermin D + H2O
-
?
-
?
3.4.22.64
gasdermin D + H2O
cleavage of gasdermin D (GSDMD) into pore-forming peptides
?
-
?
3.4.22.64
gasdermin-D + H2O
-
?
-
?
3.4.22.64
human interleukin-18 + H2O
-
?
-
?
3.4.22.64
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optimal cleavage site is IEHD, LEHD, VEHD or PEHD
?
-
?
3.4.22.64
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?
-
?
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