EC Number   |
Substrates |
Products |
Reversibility |
|---|
  3.4.21.B50 | more |
wild type DegQ exhibits a much lower proteolytic activity, and thus higher chaperone-like activity, than DegP |
? |
- |
? |
| 3.4.21.B50 | more |
the genes degQ, pps, and lpa-8 are responsible for conversion of Bacillus subtilis 168 to plipastatin production |
? |
- |
? |
| 3.4.21.B50 | more |
recombinant DegQVh can not degrade bovine serum albumin and collagen. The purified recombinant DegQVh is a protective immunogen that could confer protection upon fish against infection by Vibrio harveyi |
? |
- |
? |
| 3.4.21.B50 | more |
purified DegQ protein stimulated phosphotransfer from phospho-DegS to DegU in vitro |
? |
- |
? |
| 3.4.21.B50 | more |
model substrates are cleaved at discrete Val/Xaa or Ile/Xaa sites |
? |
- |
? |
| 3.4.21.B50 | E-cadherin + H2O |
infection of epithelial cells results in a strong E-cadherin ectodomain shedding as reflected by the loss of full length E-cadherin in whole cell lysates and formation of the soluble 90 kDa extracellular domain of E-cadherin in the supernatants of infected cells. E-cadherin cleavage is an important step in bacterial pathogenesis |
? |
- |
? |
| 3.4.21.B50 | casein + H2O |
endoprotease, active serine protease whose activity requires the integrity of the catalytic site and the PDZ domains |
hydrolyzed casein |
- |
? |
| 3.4.21.B50 | more |
DegQ may degrade transiently denatured proteins, unfolded proteins which accumulate in the periplasm following heat shock or other stress conditions, and/or newly secreted proteins prior to folding and disulfide bond formation |
? |
- |
? |
| 3.4.21.B50 | more |
DegQ is responsible for differences in expression of the bacillomycin D operon (bmy) in Bacillus subtilis MO1099 and Bacillus amyloliquefaciens FZB42. Transcription of degQ in FZB42 is driven by the stronger sigmaA promoter version, whereas Bacillus subtilis MO1099, a derivative of the strain 168, carries the defective degQ promoter version |
? |
- |
? |
| 3.4.21.B50 | more |
degQ is required for plipastatin synthesis |
? |
- |
? |
