EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   3.3.2.6 | more |
- |
Caenorhabditis elegans |
? |
- |
? |
| 3.3.2.6 | leukotriene A4 + H2O |
- |
Canis lupus familiaris |
leukotriene B4 |
- |
? |
| 3.3.2.6 | leukotriene A4 + H2O |
- |
Canis lupus familiaris |
leukotriene B4 |
i.e. LTB4, a potent inflammatory mediator originating from membrane-derived arachidonic acid |
? |
| 3.3.2.6 | more |
LTA4H is a zinc metalloprotease |
Canis lupus familiaris |
? |
- |
? |
| 3.3.2.6 | leukotriene A4 + H2O |
- |
Cavia porcellus |
leukotriene B4 |
- |
? |
| 3.3.2.6 | leukotriene A4 + H2O |
i.e. 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid |
Cavia porcellus |
leukotriene B4 |
- |
? |
| 3.3.2.6 | leukotriene A4 + H2O |
model for the binding of leukotriene A4 to the active site |
Cavia porcellus |
leukotriene B4 |
mutants of Tyr378 are able to generate, not only leukotriene B4, but also (5S,12R)-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid, in a yield of about 20-30% |
? |
| 3.3.2.6 | leukotriene A4 + H2O |
biosynthesis of leukotriene B4 |
Cavia porcellus |
leukotriene B4 |
- |
? |
| 3.3.2.6 | more |
- |
Cavia porcellus |
? |
- |
? |
| 3.3.2.6 | more |
the aminopeptidase activity accepts a variety of substrates and certain arginyl di- and tri-peptides as well as p-nitroanilide derivates of Ala and Arg |
Cavia porcellus |
? |
- |
? |
