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Results 1 - 10 of 144 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more activation of heterodimeric nuclear transcription factor NFkappaB is an essential step in inflammation, e.g. resulting in osteoarthritis, ulcerative colitis, asthma, and Crohn's disease, signalling step for phosphorylation, subsequent ubiquitination and proteolytic degradation of IkappaB, NFkappaB remains free after the reaction and is translocated to the nucleus, NFkappaB activation is also involved in development of diseases like cancer, gut ischemia-reperfusion, diabetes, or in transplant rejections, overview Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more activation of NFkappaB by the catalytic subunit IKKbeta is required for signaling via the NFkappaB pathway in acute and systemic inflammation and for tissue protection Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more defective ubiquination of the NF-kappaB essential modifier/IkappaB kinase-gamma complex leads to impaired cellular NFkappaB signalling and hypohidrotic ectodermal dysplasia with immunodeficiency HED-ID Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more enzyme is responsible for NFkappaB activation, specific inhibition of IkB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in male Sprague-Dawley rats Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more IkappaB kinases are essential key regulators of the NFkappaB pathways in the tooth development acting as stimulators, overview Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more IKK activates and regulates NFkappaB important in intracellular signalling, overview Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more IKK activates NF-kappaB through action of TNFalpha playing an important role in subsequent signaling pathways involved in e.g. apoptosis/cell survival, cell proliferation, and inflammation Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more IKK activates NF-kappaB which initiates signaling pathways that play critical roles in a variety of physiological and pathological processes, e.g. promotion of cell survival inducing production of apoptosis inhibitors in normal and cancer cells, pathways overview, IKK/NF-kappaB links inflammation to cancer, regulation of IKK, overview Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more IKK activates NF-kappaB which initiates signaling pathways that play critical roles in a variety of physiological and pathological processes, e.g. promotion of cell survival inducing production of apoptosis inhibitors in normal and cancer cells, pathways overview, IKK/NF-kappaB links inflammation to cancer, regulation of IKK, overview Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10more IKK activates TNFalpha-dependent signaling pathways inducing 5-fluoro-2'-deoxyuridine drug resistance in different cell lines, overview Homo sapiens ? - ?
Results 1 - 10 of 144 > >>