EC Number |
Substrates |
Products |
Reversibility |
---|
2.7.1.174 | CTP + 1,2-diacyl-sn-glycerol |
- |
CDP + 1,2-diacyl-sn-glycerol 3-phosphate |
- |
? |
2.7.1.174 | CTP + 1,2-diacyl-sn-glycerol |
- |
CDP + 1,2-diacyl-sn-glycerol 3-phosphate |
Dgk1p-derived phosphatidate accumulates on the nuclear membrane |
? |
2.7.1.174 | CTP + 1,2-diacyl-sn-glycerol |
in vivo functions of Dgk1p are specifically due to its diacylglycerol kinase activity |
CDP + 1,2-diacyl-sn-glycerol 3-phosphate |
- |
? |
2.7.1.174 | CTP + 1,2-dioleoyl-sn-glycerol |
the CTP transferase domain is sufficient for diacylglycerol kinase activity |
CDP + 1,2-dioleoyl-sn-glycerol 3-phosphate |
- |
? |
2.7.1.174 | dCTP + 1,2-diacyl-sn-glycerol |
both a substrate and competitive inhibitor |
dCDP + 1,2-diacyl-sn-glycerol 3-phosphate |
- |
? |
2.7.1.174 | more |
Dgk1p does not function as a CDP-DAG synthase in vivo |
? |
- |
? |
2.7.1.174 | more |
the enzyme is a bona fide substrate of casein kinase II and its phosphorylation stimulates enzyme activity |
? |
- |
- |