EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
    2.5.1.10 | (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate |
- |
Escherichia coli |
5 diphosphate + all-trans-octaprenyl diphosphate |
- |
? |
| 2.5.1.10 | (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate |
- |
Escherichia coli K12 |
5 diphosphate + all-trans-octaprenyl diphosphate |
- |
? |
| 2.5.1.10 | (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate |
reaction of EC 2.5.1.29, bifunctional farnesyl/geranylgeranyl diphosphate synthase |
Plasmodium falciparum |
diphosphate + geranylgeranyl diphosphate |
- |
? |
| 2.5.1.10 | (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate |
reaction of EC 2.5.1.29, the enzyme catalyze the sequential head-to-tail addition of three C5 molecules of isopentenyl diphosphate to dimethylallyl diphosphate with the concomitant release of pyrophosphate. Under environmental stresses, Haematococcus pluvialis accumulates large amounts of carotenoids. Scale of carotenoid biosynthesis depends on availability of geranylgeranyl pyrophosphate precursor, which is supplied by GGPP synthase through sequential 1'-4 condensation of three isopentenyl pyrophosphates into dimethylallyl pyrophosphate |
Haematococcus lacustris |
diphosphate + geranylgeranyl diphosphate |
- |
? |
| 2.5.1.10 | (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate |
reaction of EC 2.5.1.29, the enzyme catalyze the sequential head-to-tail addition of three C5 molecules of isopentenyl diphosphate to dimethylallyl diphosphate with the concomitant release of pyrophosphate |
Arabidopsis thaliana |
diphosphate + geranylgeranyl diphosphate |
- |
? |
| 2.5.1.10 | (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate |
reaction of EC 2.5.1.29, the enzyme catalyze the sequential head-to-tail addition of three C5 molecules of isopentenyl diphosphate to dimethylallyl diphosphate with the concomitant release of pyrophosphate |
Haematococcus lacustris |
diphosphate + geranylgeranyl diphosphate |
- |
? |
| 2.5.1.10 | (E)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate |
- |
Geobacillus stearothermophilus |
(E)-ethynylfarnesyl diphosphate + diphosphate |
double condensation product. Yield is 0.8% E-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate |
? |
| 2.5.1.10 | (Z)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate |
- |
Sus scrofa |
(Z)-ethynylfarnesyl diphosphate + diphosphate |
sole product with wild-type, yield is 21.9% Z-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate |
? |
| 2.5.1.10 | (Z)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate |
- |
Geobacillus stearothermophilus |
(Z)-ethynylfarnesyl diphosphate + diphosphate |
sole product with wild-type, yield is 88.8% Z-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate. Mutant Y81D yields products ethynylgeranyl, ethynylfarnesyl, and ethynylgeranylgeranyl diphosphates |
? |
| 2.5.1.10 | 8-acetoxygeranyl diphosphate + isopentenyl diphosphate |
- |
Geobacillus stearothermophilus |
diphosphate + 12-acetoxyfarnesyl diphosphate |
21.8% yield |
? |
