EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.2.29 | 2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one + tRNAguanine |
2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one appears to partition between: 1. normal turnover, 2. inactivation, 3. an alternative processing to an unidentrified fluoride-released product |
Escherichia coli |
guanine + tRNA2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one |
- |
? |
2.4.2.29 | 7-(cyano)-7-deazaguanine + tRNAguanine |
- |
Escherichia coli |
guanine + tRNA(7-(cyano)-7-deazaguanine) |
inserted 7-(cyano)-7-deazaguanine is located in the first position of the anticodon |
? |
2.4.2.29 | 7-aminomethyl-7-carbaguanine + [RNAECYMA]-2'-deoxyguanine 34 |
TGT-RNA covalent intermediate |
Escherichia coli |
guanine + [RNAECYMA]-2'-deoxy-pre Q1 |
- |
? |
2.4.2.29 | 7-aminomethyl-7-carbaguanine + [RNAECYMA]-guanine |
hairpin RNA corresponding to the tRNAtyr anticodon stem-loop motif, TGT-RNA covalent intermediate |
Escherichia coli |
guanine + [RNAECYMA]-pre Q1 |
- |
? |
2.4.2.29 | 7-aminomethyl-7-carbaguanine + [tRNA]-guanine |
the TGT-RNA covalent complex is kinetically capable of occurring on the TGT reaction pathway. Dissociation of product RNA from the enzyme is overall rate-limiting in the steady state. Role for the 2'-hydroxyl group of the ribose in the TGT reaction |
Escherichia coli |
guanine + [tRNA]-pre Q1 |
- |
? |
2.4.2.29 | 7-aminomethyl-7-carbaguanine + [tRNA]-guanine |
Tyr106 in the active site is hydrogen bonded in the ligand-free structure |
Zymomonas mobilis |
guanine + [tRNA]-pre Q1 |
- |
? |
2.4.2.29 | guanine + tRNAguanine |
- |
Escherichia coli |
tRNAguanine + guanine |
- |
r |
2.4.2.29 | guanine34 in tRNA + 7-aminomethyl-7-carbaguanine |
- |
Escherichia coli |
7-aminomethyl-7-carbaguanine34 in tRNA + guanine |
- |
? |
2.4.2.29 | guanine34 in tRNA + 7-aminomethyl-7-carbaguanine |
- |
Plasmodium falciparum |
7-aminomethyl-7-carbaguanine34 in tRNA + guanine |
- |
? |
2.4.2.29 | guanine34 in tRNA + 7-aminomethyl-7-carbaguanine |
- |
Zymomonas mobilis |
7-aminomethyl-7-carbaguanine34 in tRNA + guanine |
- |
? |