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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
2.3.1.286
2 KKGQSTSRHKKAcLMFKTEG + 2 NAD+ + 2 H2O
-
Thermotoga maritima
KKGQSTSRHKKLMFKTEG + 2''-O-acetyl-ADP-D-ribose + 3''-O-acetyl-ADP-D-ribose + nicotinamide
-
?
2.3.1.286
acetyl-CoA + [protein]-L-lysine
-
Escherichia coli
CoA + [protein]-N6-acetyl-L-lysine
-
?
2.3.1.286
acetyl-cytochrome c + NAD+ + H2O
the enzyme does not deacetylate native acetyl-cytochrome c but does deacetylate the heat-denatured substrate
Saccharomyces cerevisiae
?
-
?
2.3.1.286
acetyl-poly-L-lysine + NAD+ + H2O
-
Saccharomyces cerevisiae
?
-
?
2.3.1.286
AGG(AcK)GG(AcK)GMG(AcK)VGA(AcK)RHSC + NAD+ + H2O
tetraacetylated histone-H4 N-terminal tail peptide
Saccharomyces cerevisiae
AGG(AcK)GG(AcK)GMG(AcK)VGAKRHSC + 2''-O-acetyl-ADP-D-ribose + nicotinamide
-
?
2.3.1.286
ARTKQTAR(AcK)STGG(AcK)APRKQLC + NAD+ + H2O
diacetyl ated histone-H3 N-terminal tail peptide
Saccharomyces cerevisiae
ARTKQTARKSTGGKAPRKQLC + 2''-O-acetyl-ADP-D-ribose + nicotinamide
-
?
2.3.1.286
fluorogenic acetyl-L-lysine + NAD+ + H2O
-
Saccharomyces cerevisiae
?
-
?
2.3.1.286
HLKSKKGQSTSRHK(K-Ac)LMFK + NAD+ + H2O
p53A peptide
Archaeoglobus fulgidus
HLKSKKGQSTSRHKKLMFK + 2''-O-acetyl-ADP-D-ribose + nicotinamide
-
?
2.3.1.286
hyperacetylated histone-DNA complex + NAD+ + H2O
-
Drosophila melanogaster
deacetylated nuclease-resistant histone-DNA complex + ?
-
?
2.3.1.286
K382azaKAc-containing p53 peptide + NAD+ + H2O
-
Thermotoga maritima
K382azaK-containing p53 peptide + 2''-O-acetyl-ADP-D-ribose + nicotinamide
-
?
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