Refine search

Search Substrates and Products (Substrate)

Substrates and Products (Substrate): show results

Don't show organism specific information (fast!)

Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)

(Not possible to combine with the first option)

Refine your search

Recommended Name:

EC Number:

Commentary Substrates:

Literature (Substrates):

Organism:

Products:

Commentary (Products):

Reversibility:

Search term:

Results 1 - 3 of 3

EC Number	Substrates	Commentary Substrates	Products	Commentary (Products)	Reversibility
2.3.1.236	acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+	the multi-domain polyketide synthase involved in the synthesis of azinomycin B	5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+	-	?
2.3.1.236	acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+	-	5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+	-	?
2.3.1.236	acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+	-	5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+	incubation of substrates with isoform AziB alone leads to a truncated single-ring product, 2-methylbenzoic acid. Presence of thioesterase AziG acting as a chain elongation and cyclization domain is required for additional two rounds of chain extension to form the expected product, 5-methyl-1-naphthoate. None of the other thioesterase domains (AziA6, AziA7, AziA8) are capable of catalyzing the reaction	?

Results 1 - 3 of 3

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2026.1 (March 2026)