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Results 1 - 10 of 13 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
11-methoxy-16-epivellosimine + acetyl-CoA
-
CoA + 11-methoxy-vinorine
-
?
16-epi-vellosimine + acetyl-CoA
VS responsible for generation of the basic carbon skeleton of the target compound ajmaline, His160 and Asp164 are the most important amino acids for the catalytic process, His-X-X-X-Asp sequence together with Asp-Phe-Gly-Trp-Gly are highly conserved motifs in acyltransferases
vinorine + CoA
-
?
acetyl-CoA + 16-epivellosimine
-
CoA + vinorine
-
?
acetyl-CoA + 16-epivellosimine
-
CoA + vinorine
-
r
acetyl-CoA + 16-epivellosimine
the enzyme is involved in a crucial step of antiarrhythmic drug ajmaline biosynthesis, pathway overview
CoA + vinorine
-
r
acetyl-CoA + 16-epivellosimine
the enzyme is involved in a crucial step of antiarrhythmic drug ajmaline biosynthesis, pathway overview
CoA + vinorine
-
?
acetyl-CoA + 16-epivellosimine
the enzyme is involved in a crucial step of antiarrhythmic drug ajmaline biosynthesis, pathway overview
CoA + vinorine
-
r
acetyl-CoA + 16-epivellosimine
substrate specificity in both reaction directions, the reverse reaction is preferred
CoA + vinorine
-
r
acetyl-CoA + 16-epivellosimine
the forward reaction is preferred
CoA + vinorine
-
r
acetyl-CoA + gardneral
i.e. 11-methoxy-16-epivellosimine, sarpagan-type alkaloid
CoA + 11-methoxyvinorine
ajmalin-type alkaloid
r
Results 1 - 10 of 13 > >>