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Results 1 - 7 of 7

EC Number	Substrates	Commentary Substrates	Products	Commentary (Products)	Reversibility
2.1.1.366	more	ESET can specifically methylate histone H3 while inactive toward histone H2A, H2B and H4	?	-	?
2.1.1.366	more	H3K9 methylation by SETDB1 occurs in a distributive manner	?	-	?
2.1.1.366	S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9	-	S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9	-	?
2.1.1.366	S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9	the presence of H3K14ac is required for SETDB1 recruitment via 3TD binding to H3K9me1/2/3-K14ac regions and establishment of H3K9me3	S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9	-	?
2.1.1.366	S-adenosyl-L-methionine + [histone H3 peptide 1-15]-L-lysine9	-	S-adenosyl-L-homocysteine + [histone H3 peptide 1-15]-N6-methyl-L-lysine9	-	?
2.1.1.366	S-adenosyl-L-methionine + [histone H3 peptide 1-15]-N6,N6-dimethyl-L-lysine9	-	S-adenosyl-L-homocysteine + [histone H3 peptide 1-15]-N6,N6,N6-trimethyl-L-lysine9	-	?
2.1.1.366	S-adenosyl-L-methionine + [histone H3 peptide 1-15]-N6-methyl-L-lysine9	-	S-adenosyl-L-homocysteine + [histone H3 peptide 1-15]-N6,N6-dimethyl-L-lysine9	-	?

Results 1 - 7 of 7

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Release 2026.1 (March 2026)