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Results 1 - 4 of 4

EC Number	Substrates	Commentary Substrates	Products	Commentary (Products)	Reversibility
2.1.1.208	S-adenosyl-L-methionine + uridine2479 in 23S rRNA	AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of uridine2479 of the 23S ribosomal RNA in Gram-positive bacteria and thus mediates resistance to the oligosaccharide antibiotic avilamycin	S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA	-	?
2.1.1.208	S-adenosyl-L-methionine + uridine2479 in 23S rRNA	AviRb modifies the 2'-O-ribose position of nucleotide uridine2479 within helix 89	S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA	-	?
2.1.1.208	S-adenosyl-L-methionine + uridine2479 in 23S rRNA	-	S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA	-	?
2.1.1.208	S-adenosyl-L-methionine + uridine2479 in 23S rRNA	AviRb modifies the 2'-O-ribose position of nucleotide uridine2479 within helix 89. The exact position of the modification is conformed by MALDI mass spectrometry, a single methyl group is added. No methylation activity with 16S rRNA	S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA	-	?

Results 1 - 4 of 4

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Release 2026.1 (March 2026)