EC Number |
Substrates |
Products |
Reversibility |
---|
1.5.99.4 | (R)-nicotine + acceptor + H2O |
- |
(R)-6-hydroxynicotine + reduced acceptor |
- |
? |
1.5.99.4 | (RS)-nicotine + acceptor + H2O |
via N-methylmyosmine, which then spontaneously hydrolyzes to pseudooxynicotine. The two enantiomers are degraded at approximately the same rate, indicating that NOX does not show chiral selectivity |
pseudooxynicotine + reduced acceptor |
- |
? |
1.5.99.4 | (S)-nicotine + 2,6-dichlorophenolindophenol + H2O |
- |
(S)-6-hydroxynicotine + reduced 2,6-dichlorophenolindophenol |
- |
? |
1.5.99.4 | (S)-nicotine + 2,6-dichlorophenolindophenol + H2O |
- |
(S)-6-hydroxynicotine + reduced 2,6-dichlorophenolindophenol |
- |
r |
1.5.99.4 | (S)-nicotine + acceptor |
- |
(S)-nicotine delta1',5'-iminium ion + reduced acceptor |
- |
? |
1.5.99.4 | (S)-nicotine + acceptor + H2O |
- |
nornicotine + reduced acceptor + ? |
- |
? |
1.5.99.4 | (S)-nicotine + acceptor + H2O |
- |
nicotine-N-oxide + reduced acceptor |
- |
? |
1.5.99.4 | (S)-nicotine + acceptor + H2O |
via N-methylmyosmine, which then spontaneously hydrolyzes to pseudooxynicotine. The two enantiomers are degraded at approximately the same rate, indicating that NOX does not show chiral selectivity |
pseudooxynicotine + reduced acceptor |
- |
? |
1.5.99.4 | (S)-nicotine + brilliant cresyl blue + H2O |
- |
(S)-6-hydroxynicotine + reduced brilliant cresyl blue |
- |
r |
1.5.99.4 | (S)-nicotine + menadione + H2O |
- |
(S)-6-hydroxynicotine + menadiol |
- |
r |