EC Number   |
Substrates |
Products |
Reversibility |
|---|
   1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
- |
1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
- |
1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 |
transitional product is 6-hydroxy-N-methylmyosmine that hydrolyses spontaneously |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
- |
6-hydroxy-pseudooxynicotine + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
- |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
absolute stereospecificity on the L-form |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
absolute stereospecificity on the L-form |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
intermediate product 6-hydroxy-N-methylmyosmine, which hydrolyzes to 6-hydroxy-pseudooxynicotine |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
the enzyme catalyzes the oxidation of (S)-6-hydroxynicotine to 6-hydroxypseudooxynicotine during microbial catabolism of nicotine |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
the enzyme is essential for nicotine or (S)-6-hydroxynicotine degradation |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
the enzyme is involved in degradation of nicotine |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
- |
? |
| 1.5.3.5 | (S)-6-hydroxynicotine + H2O + O2 |
the enzyme converts (S)-6-hydroxynicotine into 6-hydroxy-N-methylmyosmine which then spontaneously hydrolyzes into 6-hydroxypseudooxynicotine. (S)-6-Hydroxynicotine is the preferred substrate in vivo. The enzyme shows no activities toward the R enantiomer of nicotine or 6-hydroxynicotine |
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 |
- |
? |
