EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.99.38 | cholesterol + AH2 + O2 |
- |
Bos taurus |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
- |
Canis lupus familiaris |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
- |
Equus caballus |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
- |
Gallus gallus |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
- |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
cholesterol 25-hydroxylase has the capacity to play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein processing and ultimately leads to inhibition of gene transcription |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
genetic variability in the set of cholesterol metabolism genes: cholesterol 25-hydroxylase, cholesterol 24-hydroxylase and ATP-binding cassette transporter A1 does not influence the development of Alzheimers disease |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
the enzyme has the capacity to synthesize an active and potent regulator of the sterol response element binding protein pathway within the cell |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
lower 25-hydroxylation enzyme activity by CYP1A2 compared to marker enzyme CYP3A4 |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
lower 25-hydroxylation enzyme activity by CYP2C9 compared to marker enzyme CYP3A4 |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |