EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.12.98.3 | more |
no growth on H2-CO2, inability to metabolize hydrogen, the lack of hydrogenase activity in Methanosarcina acetivorans extracts is not due to obvious mutations in either the coding regions or the promoters, hydrogenases are inactivated at the level of transcription and/or translation, Methanosarcina acetivorans possesses the machinery to express hydrogenases, although it does not express its own hydrogenases. This is consistent with specific inactivation of the Methanosarcina acetivorans hydrogenase promoters and highlight the importance of testing hypotheses generated by using genomic data |
Methanosarcina acetivorans |
? |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
- |
Methanosarcina barkeri |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
no activity with ferredoxin |
Methanosarcina barkeri |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
enzyme is part of a membrane-bound electron transport system in methanogenesis |
Methanosarcina barkeri |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | more |
growth on H2-CO2 |
Methanosarcina barkeri |
? |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
- |
Methanosarcina mazei |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
enzyme is part of a membrane-bound electron transport system in methanogenesis |
Methanosarcina mazei |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
coenzyme F420-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred. The electrochemical proton gradient thereby generated drives ATP synthesis from ADP and diphosphate |
Methanosarcina mazei |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | H2 + 2-(2,3-dihydropentaprenyloxy)phenazine |
cofactor F420(H2)-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred |
Methanosarcina mazei |
2-dihydropentaprenyloxyphenazine |
- |
? |
1.12.98.3 | H2 + 2-hydroxyphenazine |
- |
Methanosarcina mazei |
dihydro-2-hydroxyphenazine |
- |
? |