EC Number |
Recommended Name |
Substrates |
Organism |
Products |
---|
2.8.2.4 | estrone sulfotransferase |
3'-phosphoadenylylsulfate + estrone |
- |
Homo sapiens |
adenosine 3',5'-bisphosphate + estrone sulfate |
2.8.2.4 | estrone sulfotransferase |
3'-phosphoadenylylsulfate + estrone |
- |
Homo sapiens |
adenosine 3',5'-bisphosphate + estrone 3-sulfate |
2.8.2.14 | bile-salt sulfotransferase |
3'-phosphoadenosine-5'-phosphosulfate + oestrone |
- |
Homo sapiens |
adenosine 3',5'-bisphosphate + estrone sulfate |
2.8.2.15 | steroid sulfotransferase |
3'-phosphoadenylylsulfate + estrone |
- |
Homo sapiens |
adenosine 3',5'-bisphosphate + estrone sulfate |
2.8.2.34 | glycochenodeoxycholate sulfotransferase |
3'-phosphoadenylyl 5'-phosphosulfate + estrone |
- |
Homo sapiens |
adenosine 3',5'-bisphosphate + estrone 7-sulfate |
3.1.6.2 | steryl-sulfatase |
estrone 3-sulfate + H2O |
- |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone 3-sulfate + H2O |
hydrolyzes estrone 3-sulfate to its active, unsulfated form |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate |
- |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
- |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
natural substrate |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
only s-form |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
STS converts the major circulating plasma estrogen estrone sulfate into the biologically active estrogene estrone, STS plays an important role in the in situ estrogen actions of various sex steroid-dependent tumors, peripheral STS plays a very important role in peripheral estrogen metabolism and actions in the human fetus |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
STS plays an important role in the in situ estrogen actions of estrogen-dependent human tissues and various sex steroid-dependent tumors, STS may be associated with the degree of atherosclerotic changes in the female aorta, transformation of the biologically inactive form of plasma estrogen in its active form |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
0.6% of the activity with cholesterol sulfate |
Homo sapiens |
estrone + sulfate |
3.1.6.2 | steryl-sulfatase |
estrone sulfate + H2O |
estrone is locally produced from circulating inactive estrone sulfate by steroid sulfatase |
Homo sapiens |
estrone + sulfate |
3.2.1.21 | beta-glucosidase |
estrone-3-beta-D-glucoside + H2O |
poor activity |
Homo sapiens |
beta-D-glucose + estrone |
5.1.99.2 | 16-hydroxysteroid epimerase |
16alpha-Hydroxyestrone |
- |
Homo sapiens |
16beta-Hydroxyestrone |
7.6.2.2 | ABC-type xenobiotic transporter |
ATP + H2O + estrone-3-sulfate/in |
- |
Homo sapiens |
ADP + phosphate + estrone-3-sulfate/out |
7.6.2.2 | ABC-type xenobiotic transporter |
ATP + H2O + estrone-3-sulfate[side 1] |
- |
Homo sapiens |
ADP + phosphate + estrone-3-sulfate[side 2] |
7.6.2.2 | ABC-type xenobiotic transporter |
ATP + H2O + estrone-3-sulfate[side 1] |
substrate for BCRP |
Homo sapiens |
ADP + phosphate + estrone-3-sulfate[side 2] |
7.6.2.2 | ABC-type xenobiotic transporter |
ATP + H2O + estrone[side 1] |
substrate for MRP1 |
Homo sapiens |
ADP + phosphate + estrone[side 2] |
7.6.2.3 | ABC-type glutathione-S-conjugate transporter |
ATP + H2O + S-(estrone 3-sulfate)glutathione[side 1] |
substrate for isoform MRP1 |
Homo sapiens |
ADP + phosphate + S-(estrone 3-sulfate)glutathione[side 2] |
7.6.2.3 | ABC-type glutathione-S-conjugate transporter |
ATP + H2O + S-(estrone-3-sulfyl)glutathione[side 1] |
- |
Homo sapiens |
ADP + phosphate + S-(estrone-3-sulfyl)glutathione[side 2] |